Lots of mods can only be run on the longer-standing Forge, so you may end up wanting to use Forge simply so you can use all the mods you want. The choice of which mod loader is best for you depends on which mods you want to use. Only certain mods, such as Optifine, can run without a modloader.
To install most Minecraft mods, you'll need a modloader like Forge or Fabric. Forge or Fabric: which Minecraft mod loader should you use?